Katia Vega, Nan Jiang, Xin Liu, Viirj Kan, Nick Barry, Pattie Maes, Ali Yetisen, Joe Paradiso. " The dermal abyss: interfacing with the skin by tattooing biosensors." Proceedings of the 2017 ACM International Symposium on Wearable Computers, ISWC '17 , p. 138-145, 2017.

Abstract

The Dermal Abyss (d-abyss) presents an approach to biointerfaces in which the body surface is rendered as an interactive display by patterning biosensors into the skin to produce color changes in response to biomarker variations in the interstitial fluid. It combines advances in biotechnology with traditional methods in tattoo artistry. d-abyss is designed to use the aesthetics, permanence, and visible nature of tattoos to encode information. In the present work, we replace traditional inks with colorimetric and fluorescent biosensors that can report on the concentration of sodium, glucose, and pH in the interstitial fluid of the skin. We report the preliminary evaluation of these biosensors in an ex vivo skin model, assessing their visibility from the dermis. We describe different applications of d-abyss in the medical, lifestyle, and security domains. This work is a proof of concept of a platform in which the skin reveals information inside the body, tattoos form wearable displays within the skin, and the body's metabolism works as an input for the d-abyss biosensors.