Dissertation Title: Establishing Peromyscus leucopus as a Model Organism using Novel Camera-Based Reproductive Techniques

Abstract: 

This thesis proposes the development of non-invasive reproductive techniques and genomic tools to establish Peromyscus leucopus as a viable model organism for biomedical research. The specific aims are to optimize camera-based estrous tracking for reproductive management and to implement CRISPR/Cas9 technologies for precise genetic modifications. This research is expected to provide significant insights into the genetic basis of disease resistance and longevity, facilitating broader applications in human health and disease studies.

Committee members:
Kevin Esvelt, Assistant Professor, MIT Media Lab
Sam Telford, Professor, Department of Infectious Disease and Global Health, Tufts University
Kenneth Oye, Professor, School of Humanities Arts and Social Sciences, MIT